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Planning

Thursday, October 5, 2023

Time Event  
08:30 - 09:00 Welcome coffee - .  
09:00 - 09:15 Openning introduction - Sandrine Lacombe & Martin Pruschy  
09:15 - 09:45 ***Invited*** Radiomics for radio-immunotherapy combinations: towards ultraprecision medecine? - Roger Sun  
09:45 - 10:15 ***Invited*** The use of organoids in radiotherapy research - mechanisms, prediction and regeneration - Rob Coppes  
10:15 - 10:25 Radiotherapeutic Efficiacy of anti-KRAS Intracellular Radioimmunoconjugates in Pancreatic Adenocarcinoma - João Lourenço  
10:25 - 10:35 Caffeic Acid Phenethyl Ester (CAPE), a natural radiosensitizer for lung adenocarcinomas - Elia Prades Sagarra  
10:35 - 10:45 Targeting exostosin glycosyltransferase 2 (EXT2) modulates glioblastoma cell metabolism, sensitizing to X-ray irradiation via ferroptosis - Rocio Matesanz Sanchez  
10:45 - 10:55 Anti-cancer and radio-sensitizing properties of new bimetallic (N-Heterocyclic Carbene)-amine-Pt(II) complexes - Sophie Bombard  
10:55 - 11:25 Coffee break  
11:25 - 11:55 ***Invited*** The radiation-induced ATM nucleoshuttling (RIANS) model : a survey of the radiosensitivity of human tumor and healthy tissues - Nicolas Foray  
11:55 - 12:05 DNA-PK as a target for radiosensitization in high-risk Group 3 Medulloblastoma. - Eleanor Hawkins  
12:05 - 12:15 Importance of Homologous Recombination Pathway for the Repair of DNA Damage Induced by Proton Beam Irradiation - Razan Hessenow  
12:15 - 12:25 Targeting the survival kinase DYRK1B: A novel approach to overcome radiotherapy-related treatment resistance - Claire Becker  
12:25 - 12:35 The unique tumour radiosensitizer AsiDNA protects the normal tissue against chemo- and radio-induced toxicity. - Anouk Sesink  
12:35 - 14:00 Lunch  
14:00 - 15:00 Round table - Translational Radiobiology: Future Directions - Martin Pruschy, Ludwig Dubois, Verena Jendrossek  
15:00 - 15:10 Developing modulators of tumour hypoxia through inhibition of cellular oxygen consumption - Nicole Machado  
15:10 - 15:20 Overcoming radioresistance in Ewing Sarcoma induced by chronic cycling hypoxia through targeting metabolic plasticity - Safa Larafa  
15:20 - 15:30 Impact of Ionizing Radiation on the Energy Metabolism of Normal and Tumor Cells in the Brain - Marvin Kreuzer  
15:30 - 15:40 Combined sertraline/chloroquine treatment for serine/glycine producing glioblastomas. - Anais Sanchez Castillo  
15:40 - 16:10 Coffee break  
16:10 - 16:40 ***Invited*** Improving the cooperation of radiation therapy and immunotherapy in the tumor microenvironment - Sandra Demaria  
16:40 - 16:50 Targeting tumor associated macrophages improves the response of subcutaneous murine head and neck tumor to fractionated radiotherapy in vivo - Irène Bocci  
16:50 - 17:00 Low doses of irradiation remodel the immune infiltrate and control tumor growth in pediatric rhabdoid tumors - Sara Chabi  
17:00 - 17:10 Therapeutic targeting of neuropilin-1 reduces the contribution of M2-polarized macrophages to radiation-induced lung fibrosis - Lena Gockeln  
17:10 - 17:20 Long non-coding VIM-AS1: potential biomarker of fibrosis susceptibility after radiation therapy and promoter of TGFB1–driven fibrosis - Michèle Martin  
17:20 - 17:30 Metastasis: a side effect of low-dose ionizing radiation in breast cancer cells? - Justin Rondeau  
17:30 - 19:00 MSCA Fellowship dating - An afterwork dedicated to PhD students who are looking for their next fellowship position and would like to go for a MSCA Fellowship funding scheme.  

Friday, October 6, 2023

Time Event  
08:30 - 09:00 Welcome coffee - .  
09:00 - 09:30 ***Invited*** Laser Plasma Accelerator for VHEE-RT: the ebeam4therapy project - Victor Malka  
09:30 - 09:40 Development and validation of Very High Energy Electrons dose calculation in the open source matRad treatment planning toolkit - Mateusz Sitarz  
09:40 - 09:50 A novel laser-driven electron acceleration scheme based on a plasma-mirror injector - Thomas Clark  
09:50 - 10:00 Ultra-high dose rate effects on Fricke dosimeter with laser driven high energy electrons - Abhishek Panchal  
10:00 - 10:30 ***Invited*** High frequency VHEE laser driven sources - Leonida A. Gizzi  
10:30 - 10:40 Feedbacks on the installation and preliminary tests of the FLASHKNiFE, a UHDR radiotherapy system, at the Gustave Roussy Hospital - Julie Colnot  
10:40 - 10:50 FLASHlab@PITZ: R&D platform for electron UHDR and FLASH radiation biology at PITZ, DESY - Anna Grebinyk  
10:50 - 11:20 Coffee break  
11:20 - 11:30 Impact of UHDR irradiation on circulating lymphocytes in brain tumours - Development of a dosimetric tool - François de Kermenguy  
11:30 - 11:40 Fast plastic scintillators and SiPM based devices for FLASH beam monitoring - Victor Buridon  
11:40 - 11:50 Performance evaluation of EBT3, EBT-XD, and OrthoChromic OC-1 Films for Absolute Dose measurement in Electron Beams radiotherapy - Cathyanne Schott  
11:50 - 12:10 ***Invited*** Minibeam radiation therapy: divide and conquer - Yolanda Prezado  
12:10 - 12:20 Exploring the FLASH dose rate definition for proton Pencil Beam Scanning radiation therapy under a physicochemical model of reaction kinetics - Flavia Gesualdi  
12:20 - 12:30 Investigation of the chemistry occuring in the Bragg Peak of High Energy Proton Track-end using a high Resolution Imaging device - Julien Audouin  
12:30 - 12:40 Neon MiniBeam Radiotherapy: A Promising Renewed use of Heavy Ions in Cancer Treatment - Angela Corvino  
12:40 - 14:00 Lunch  
14:00 - 14:30 ***Invited*** Overview of Nanoparticle clinical experiments - Ross Berbeco  
14:30 - 14:40 The first-in-class radioenhancer NBTXR3: from cancer cell destruction to antitumor immune response activation - Sébastien Paris  
14:40 - 15:00 ***Invited*** Nanoparticles: understanding fundamentals to personalize applications - Erika Porcel  
15:00 - 15:10 Clinical transfer of AGuIX®-based radiation treatments for locally advanced cervical cancer: MR quantification and in vitro insights in the NANOCOL clinical trial framework - Pauline Maury  
15:10 - 15:20 Optimized core-shell metal organic frameworks (MOFs) with potential for chemo- and radiotherapy - Mengli DIing  
15:20 - 15:50 Coffee break  
15:50 - 16:20 ***Invited*** A novel platform for precision image-guided proton irradiation of small animals - Katia Parodi  
16:20 - 16:40 ***Invited*** Advanced functional PET Imaging in nanoparticle-augmented radiotherapy application - Charles Truillet  
16:40 - 16:50 Exploiting the power of PDT with nanomedicine and radiotherapy - Robert Griffin  
16:50 - 17:00 Ultra-small Platinum-based coordination nanoparticles for radiotherapy - Riya George  
17:00 - 17:10 Improved outcomes of radiation therapy with targeted theranostic Bismuth and Gadolinium based nanoparticles - Lena Carmes  
17:10 - 17:20 Harnessing molecular activation upon ionizing radiations for theranostic site-directed - Guillaume Bort  
19:30 - 23:00 Gala Dinner on the River Seine - Enjoy a 3h cruise on the river Seine sharing a nice Dinner, listening to a great quartet, and soaking in the amazing Paris by night.  

Saturday, October 7, 2023

Time Event  
09:00 - 09:30 Welcome coffee - -  
09:30 - 10:00 ***Invited*** Overview of AI based strategies - Maria Vakolopoulou  
10:00 - 10:20 ***Invited*** Towards AI-driven immunoradiotherapy - Charlotte Robert  
10:20 - 10:30 A common [18F]-FDG PET radiomic signature to predict survival in patients with HPV-induced cancers - Stéphane Niyoteka  
10:30 - 10:40 Analysis of the interferon gamma response in non-tumor human lung in response to radiation - Juliette Soulier  
10:30 - 10:50 ***Invited*** AI assisted theoretical predictions of electronic stopping power in complex biological structures - Aurélien de la Lande  
10:50 - 11:20 Coffee break  
11:20 - 12:20 Round table - Towards future challenges and new European projects - Maria Vakalopoulou, Charlotte Robert, Aurélien de la Lande  
12:20 - 12:30 Student prize - General conclusion  
  
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